SPE-03
8-Channel High Efficiency Automated SPE System
The SPE-03 is a powerful and efficient automated solid phase extraction system capable of processing up to 8 samples at a time. It can be used for large and small volume water, food, soil, fuel, protein and forensics sample extraction and clean up. Like all our systems, it utilizes positive pressure to deliver fluids at fixed flow rates and prevent build up in your SPE cartridges. All samples start and finish at the same time.
Our flow path integration technique gives the SPE-03 a very small footprint and can easily fit in any fume hood. Special features include bottle rinsing, separate waste outlets and nitrogen drying.
This fully automated SPE system is the top choice for PFAS following EPA Methods 533/537/1633, DoD QSM 5.3 Table B-15, ISO 21675 and various proprietary methods. Other applications include 1-4 Dioxane, pesticides, PCBs, PAHs, mycotoxins and more.

Applications
The SPE-03 system is designed to support a wide range of analytical applications, offering flexibility and reliability for diverse testing needs.
Pesticides/PAHs/PCBs
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EPA Method 608.3
Basic/Neutral/Acidic compounds
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TCLP semi-volatiles per EPA Methods 8270/3535
Different sample loading options based on your application:
Special Features
Sample Container Compatibility
The SPE-03 includes tubing with needle heads to accommodate open containers up to 1L. The optional MOD-004 sample bottle rack can be used for bottles from 125mL to 1L.
Sample and solvent wastes exit through their respective tubing. This ensures that organic and aqueous wastes can be disposed of separately.
Sample/Solvent Waste Outlets
Nitrogen drying of sorbent material can be programmed into the methods. This step can be time-controlled or until the user wishes to resume. The flow meter can be adjusted up to 2.4L/min.
Nitrogen Drying
Two solvents can be mixed at specified ratios for cartridge conditioning, washing or elution. This can also be used to achieve stepped gradient elution.
Solvent Mixing
The SPE-03 can rinse sample containers using 1 or 2 solvents and then add the rinsate back to the SPE columns to improve recovery. The optional MOD-004 sample bottle rack can enable rinsing of large sample bottles.
Sample Container Rinsing
The SPE-03 uses an innovative adapter to accomodate 1, 3, 6mL SPE columns. There is no need for extra adapters.
SPE Column Compatibility
Sample capacity | 8 samples in parallel |
Sample volume | 0.5-4000 mL |
SPE column sizes | 1/3/6 mL |
Solvent capacity | 6 solvents |
Fractions | 2 for each sample |
System control | 5" resistive touch screen |
Dimensions | 35 cm x 35 cm x 45 cm |
Weight | 12 kg |
Sample capacity | 8 samples in parallel |
Sample volume | 0.5-4000 mL |
SPE column sizes | 1/3/6 mL |
Solvent capacity | 6 solvents |
Fractions | 2 for each sample |
System control | 5" resistive touch screen |
Dimensions | 35 cm x 35 cm x 45 cm |
Weight | 12 kg |

SPE-03 Case Study


York Analytical Laboratories, now part of ALS, is the first PFAS lab in New York City and one of the leaders in environmental testing, recognized for their comprehensive PFAS solutions and turnaround time. As one of the earliest adopters of SPE automation, they leveraged the SPE-03 since 2019 to handle their full range of PFAS samples. With strong leadership and foresight, York successfully expanded its operation to 3 locations in 2023, supporting drinking water, surface water and wastewater applications through their growing fleet of SPE-03 systems.
PromoChrom proudly supports their PFAS testing with our automation, ensuring high throughput and compliance with new EPA methods and evolving regulations.

PFAS Drinking Water Lab
in Tom's River, NJ

PFAS Non-Potable Waters and Solids Lab in Queens, NY
An In-Depth Look at York's EPA 1633 PFAS Workflow
How the SPE-03 Supports York's PFAS testing efforts:
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Automated processing to maximize throughput
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Enhanced efficiency with minimal supervision
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Handles complex matrices better than manifold
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Quick and effective support from PromoChrom’s dedicated team
Automate PFAS extraction with the SPE-03 following:
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EPA Method 537.1
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EPA Method 533
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EPA Method 1633
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EPA Method 537m