EPA Method 1633 doesn’t permit separate filtration steps, as they can risk leaving analytes behind if only the filtrate is extracted. This method was developed through a traditional manifold extraction procedure, where filtration would have been an entirely separate process. This sometimes leads to questions about how PromoChrom automated SPE systems handle dirty samples while adhering to the method’s guidelines.
Our automated SPE systems feature inline anti-clogging solutions that disperse sample particulates while simultaneously performing solid phase extraction. During the rinsing steps of EPA Method 1633, solvents are passed through the anti-clogging tips and inline filters to recover analytes. This is similar to implementing glass wool to help with sample flow while undergoing the same solvent rinses.
As EPA Method 1633 targets non-drinking water samples, practical implementations need to be in place to address these challenging matrices. The use of our automated extractors with anti-clogging solutions has helped major PFAS labs, including the EPA, tackle this method and receive accreditation.
Have more questions about your PFAS workflow or SPE automation? We’re here to help. Prep PFAS with PromoChrom!
Comments